Ryan is the youngest of little joe babies & is Captain hicks'Deuce". Ryan is probably best known for the movie Van Wilder by National Lampoon, though he also starred for four years in the American TV series Two Guys, a Girl and a Pizza Place playing med student Michael Bergen (nicknamed Berg). Ryan had a cameo in 2004's Harold & Kumar Go to White Castle playing a male nurse, and has appeared in The In-Laws, with Michael Douglas and Albert Brooks, and the Canadian production Foolproof (2003). In 2004, he co-starred in the action/horror flick Blade: Trinity, as Hannibal King. His latest film role sees him playing George Lutz in the 2005 remake of The Amityville Horror.

In December 2004, David Goyer (writer of the Blade trilogy and Batman Begins) announced plans to write and direct a major motion picture starring Reynolds as the Wally West version of the Flash. The film will be released by Warner Bros. sometime in 2006.

He is engaged to marry singer Alanis Morissette, with whom he lives in Ottawa, Ontario, Canada in the penthouse suite of newly-built lofts downtown and in Los Angeles, California, USA.

Filmography
Blowback (2006) (announced) Chaos Theory (2006) (pre-production) Horrible Bosses (2006) (pre-production) Ride Along (2006) (pre-production) Just Friends (2005) (completed) - Chris Waiting... (2005/I) - Monty The Amityville Horror (2005) - George Lutz School of Life (2005) (TV) - Michael "Mr. Five hundred" D'Angelo Blade: Trinity (2004) - Hannibal King Harold & Kumar Go to White Castle (2004) - Male Nurse Zeroman (2004) TV Series (voice) - Ty Cheese Foolproof (2003) - Kevin The In-Laws (2003/I) - Mark Tobias Buying the Cow (2002) - Mike Hanson Van Wilder (2002) - Van Wilder Finder's Fee (2001) - Quigley We all fall down (2000) - Red Shoes Big Monster on Campus (2000) - Karl O'Reilly Dick (1999) - Chip Coming Soon (1999/I) - Henry Lipschitz Tourist Trap (1998/I) (TV) Two Guys, a Girl and a Pizza Place (1998) TV Series - Berg The Alarmist (1997) - Howard Ancona In Cold Blood (1996) (TV) - Bobby Rupp Sabrina the Teenage Witch (1996) (TV) - Seth When Friendship Kills (1996) (TV) - Ben Colson Serving in Silence: The Margarethe Cammermeyer Story (1995) (TV) - Andy My Name Is Kate (1994) (TV) - Kevin Bannister Ordinary Magic (1993) - Ganesh/Jeffrey The Odyssey (1992) TV Series - Macro Fifteen (1990) TV Series - Billy Simpson